To Whom it May Concern,

In cases of emerging viral pathogens such as Monkeypox Virus, when there is no test that can be conducted to validate the efficacy of a disinfectant, the US Environmental Protection Agency utilizes their Emerging Viral Pathogens Policy to determine the expected efficacy of a disinfectant against an emerging virus. In the case of an enveloped virus such as Monkeypox Virus, the following criteria are used to determine efficacy of a disinfectant upon enactment of the Emerging Viral Pathogens Policy:

1. The product must be a hospital or broad-spectrum disinfectant product registered with the EPA.
2. The product must have acceptable efficacy data previously submitted to and reviewed by the

   Agency against at least one non-enveloped virus, which is considered to be more resistant to disinfectants compared to enveloped viruses such as Monkeypox Virus.

The Rejuvenate line of disinfectants (including Rejuvenate Concentrate, Ready-to-Use liquid and Wipes) fulfill these criteria and therefore can be used against Monkeypox Virus on hard, non-porous surfaces as part of a facility’s infection prevention and control protocols. Rejuvenate Concentrate (EPA Reg. No. 74559-4) should be applied at a 1:16 dilution for a contact time of five minutes. Rejuvenate Ready-to-Use liquid (EPA Reg. No. 74559-1) and Wipes (EPA Reg. No. 74559-3) should be applied with a one-minute contact time. To learn more about this ongoing situation as it unfolds, please refer to the CDC’s information page at the following link: https://www.cdc.gov/poxvirus/monkeypox/outbreak/current.html.

Should you require any further information, please do not hesitate to contact us at 1-800-387-7578. Best regards,

Junette D. Tabadero

Director, Regulatory Affairs Virox Technologies Inc.